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An NIH-funded blinded RCT is underway, using FMT via colonoscopy with donor or recipient stool for transplant (Colleen Kelly, Lawrence Brandt, personal communication). A probiotic is a living organism that, when ingested, is beneficial to the host. Several probiotics have been tested in patients with RCDI, always as an adjunct to antibiotics. In one study, the yeast Saccharomyces boulardii resulted in fewer recurrences in a group of patients with RCDI (35 vs.